Recent Publication in Science Translational Medicine

Maria Pereira and Lino Ferreira are co-authors of a recent publication in Science Translational Medicine. The work has been performed in collaboration with Jeff Karp and Pedro del Nido at Harvard. The work describes a bioinspired elastic, biodegradable and biocompatible tissue adhesive based on poly(glycerol-co-sebacate) acrylate (PGSA) that can be activated by UV light providing strong adhesion to dynamic tissues. PGSA presents better biocompatibility than cyanoacrylate adhesives and provided a hemostatic seal when applied to large blood vessels and cardiac wall defects. PGSA coated patches were attached on the interventricular septum in a chronic porcine beating heart model and resisted supraphysiologic pressures.

By | 2017-03-19T22:54:21+00:00 January 12th, 2014|Publications|0 Comments