We use many approaches to answer our research questions, including the design of new biomaterials (nanoparticles, microparticles, gels, coatings, etc…) with relevant biological information, molecular and cell biology, microfluidic systems, high content analysis, and animal experimentation.
We have designed nanomaterials that can be monitored by Magnetic Resonance Imaging (MRI) and efficiently deliver miRNAs within cells, nanomaterials that can release efficiently hydrophobic small molecules such as retinoic acid, gels to efficiently transplant stem cells in chronic wounds, etc…
We use molecular analysis to identify signaling pathways that are activated when cells are exposed to specific signals or extracellular matrixes.
We have high experience in the differentiation of pluripotent stem cells into vascular lineages (endothelial and smooth muscle cells).
We are also working with disesase-specific induced pluripotent stem cells (iPSCs) that can provide insights into the mechanisms underlying cardiovascular diseases.